Fish oil supplements particularly if they also include Vitamin B12 can alleviate menstrual discomfort in young women. Menstrual pain is generally attributed to prostaglandins. (PG) hence the efficiency of NSAIDS, which inhibits their synthesis. However the PG's most likely to blame are those derived from Omega -6 LC PUFA. Rather than those of the Omega-3 Series, which are less biologically active. Indeed there is evidence that levels of dietary Omega-3 LC PUFA are lower in women with, than without Dysmenorrhea. Fish oil plus vitamin B12 should be superior to fish oil alone. Possibly the vitamin is involved in the prostaglandin metabolism or has antioxidant effects. They conclude that the supplementations with Omega-3 LC PUFA and vitamin B12 may server as an alternate treatment to NSAID medication against Dysmenorrhea in young women. Two important advantages are, combination appears to be essentially without adverse effects, and it is easy to administer.
Dyslexia is a fairly common condition, which involves difficulties in learning to read and write, mirror reversals of letters and words, and poor short-term memory. Dyslexia is closely related to dysphasia (problems with coordination and muscle control) and attention-deficit hyperactivity disorder. It is estimated that about 10% of the populations of the United States and the United Kingdom suffer from dyslexia and 4% are severely affected. There was a 3-fold increase in the prevalence of learning disorders in the USA over the period 1976 to 1993 and 80% of the new cases involved dyslexia.
Dr. Jacqueline Stordy of the University of Surrey believes that dyslexia, dyspraxia, and attention-deficit hyperactivity disorder have one common denominator - a deficiency of long-chain fatty acids. She points to a study which found improved dark adaptation (a problem among dyslexics) after supplementation with 480 mg/day of docosahexaenoic acid (a main constituent of fish oil) for a month. Another study involving 15 dysphasic children found that supplementation with a proprietary mixture of tuna oil, evening primrose oil, thyme oil, and vitamin E for 4 months markedly improved their motor skills. The mixture provided 480 mg of docosahexaenoic acid, 35 mg of arachidonic acid, 96 mg of alpha-linolenic acid, 80 mg of vitamin E, and 24 mg of thyme oil daily. Dr. Stordy concludes that long-chain polyunsaturated fatty acid supplements may benefit children with dyslexia, dyspraxia, and attention-deficit hyperactivity disorder and notes that large, double-blind, placebo-controlled studies are already underway to verify this hypothesis.
Researchers at the National Institute of Alcohol Abuse and Alcoholism believe that the increasing rates of depression seen in North America over the last 100 years are due to a significant shift in the ratio of n-6 (arachidonic acid, linoleic acid) to n-3 (docosahexaenoic acid, linolenic acid) fatty acids in the diet. The human race evolved on a diet having a ratio of about 1:1 of these acids; it is now estimated to be between 10:1 and 25:1. Docosahexaenoic acid (DHA) is a main component of the synaptic membranes and a lack of it has been linked to depression. Fish oils are a rich source of DHA and it can also be biosynthesized in the body from linolenic acid. The researchers speculate that the depressions which often accompany alcoholism, multiple sclerosis, and childbirth (postpartum depression) are all due to a lack of DHA and can be corrected by increasing the dietary intake of DHA or linolenic acid (seal oil). They also point out that depression and coronary heart disease are strongly associated and that a low intake of n-3 fatty acids has been linked to both.
Diabetes is a disorder characterized by high blood levels of glucose in the blood. Diabetes can damage the large blood vessels increasing the risk of stroke, heart attack, and in the limbs, can lead to gangrene. Many studies now suggest that omega-3 is invaluable in combating circulation problems associated with diabetes by rendering the walls of the veins and arteries smoother and more elastic.
In another study published in 1994 by the British Nutrition Foundation they reported that daily consumption of seal oil (high in omega 3), by Alaskan natives led to a 20% lowering of glucose intolerance and diabetes.
- Adler, Boyko, Schraer, Murphy, 1994 Nutrition Supplement
A recent study published by Tokyo Medical and Dental University, indicates that the DPA component of the omega 3 can be more than TEN TIMES AS EFFECTIVE as EPA in helping to heal damaged blood vessels, seal oil is the ONLY supplement rich in natural DPA.
Eczema is a skin disease, especially conditions that cause dry scaly skin like eczema often result from excessive levels of 'bad' eicosanoids (Omega-6 PGE 2 series). While eczema is not life threatening, it is a cause of concern because it indicates that a significant inflammatory process is already taking place in the skin. Research shows eczema stems from the overproduction of 'bad' eicosanoids called leukotrienes. Reducing Arachidonic acid levels by using high dose marine oil chokes off the production of leukotrienes, while simultaneously increasing the levels of 'good' eicosanoids. Dermatologists usually prescribe corticosteroid creams to reduce inflammation, but these drugs unfortunately knock out 'good and bad' eicosanoids and that leads to a thinning of the skin. Various studies have indicated that high dose marine oil, without the use of corticosteroid, can contribute to some improvement in eczema.
Fatty liver in patients is most commonly found in the early stages of cirrhosis of the liver with or without excessive alcohol involvement. Fatty liver is also commonly associated with liver pathologies and metabolic disturbances with obesity, diabetes, hyperlipidemia, and exposure to certain toxins.
Fatty liver is defined as lipid infiltration in more than 50% of hepatocytes mainly in the form of big lipid droplets. In patients with fatty liver, recent clinical research has found that the concentration of the long chain Omega 3 fatty acid is very low. Also, research has found that an increase in fat droplet size in hepatocytes is associated with a decrease of the percentage of Omega 3 in the liver triglycerides.
The most common cause of fatty liver today is chronic alcoholism, where the alcohol damages liver cells and causes malfunction of the liver metabolism. This in turn causes lipid, carbohydrates and protein metallic disturbances. Overeating increase lipid carbohydrates and protein intake compound this. Most commonly this patient will develop obesity, hyperlipidemia, insulin resistance, hypertension and visceral distribution of the adipose tissue.
Recent clinical findings have found patients with end-stage liver disease manifest a wide variety of functional abnormalities that eventually lead to their deaths. Such patients also have low levels of polyunsaturated fatty acids (PUFA) of carbon lengths 20 or greater in plasma. (C20:5W-3 EPA, C22:5W-3 DPA, C22:6W-3 DHA). This is due to hepatic damage and impairment of the 20-22 carbon PUFA from their fatty acids 18 (alpha linolenic acid) carbon dietary precursors. This normally takes place principally in the liver.
Long chain Omega 3 fatty acids have been proven to decrease the LDL cholesterol (low density lipoprotein), serum triglycerides, platelet aggregability, blood viscosity, hypertension, glycerolipid synthesis, and reduce the fatty droplet deposit to the liver. These fatty acids have also been shown to improve the insulin resistance, liver function, and enhance red cell deformability. In addition, they alter the cellular membrane phospholipids Omega 3 fatty acid concentration, which increases the cellular metabolic rate as well as cellular functions. Therefore, directly and indirectly Omega 3 long chain polyunsaturated fatty acids (Seal Oil) improves the general condition of the liver and can effectively treat or even prevent the occurrence of fatty liver. Because fatty liver is a malfunction of the liver as well as a disturbance of metabolism of fat, protein and carbohydrates overeating and overindulgence of alcohol should be eliminated.
Post Viral Fatigue CFIDS (chronic fatigue and immune dysfunction syndrome) is an illness characterized by a number of symptoms rather like a severe flu. It affects the body and the mind. It is also known as post viral fatigue syndrome (PVFS) and Fibromyalgia. It has probably been in existence for many years, but it is poorly understood and has been called by different names at different times.
The characteristic features are fatigue, which goes on for more than 6 months and for which no other cause can be found. It may follow an infection like flu or tonsillitis. The fatigue affects both mental and physical activity and is not relieved by rest. Other symptoms may include sweating, shivering, feeling cold, headaches and nausea. Bowel problems such as diarrhea or constipation can occur. Visual problems and generalized aches and pains especially in muscles or joints may occur. Patients complain of poor memory and difficulty in concentrating.
All these symptoms may vary from day to day and are often made worse by minimal physical or mental effort. Mood swings may occur and people may feel tearful and depressed. Patients become particularly frustrated that no clear explanation for their illness can be found. They are also somewhat characteristically "high achievers" who were more energetic than average prior to becoming ill.